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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SNAP23
All Species:
23.64
Human Site:
S116
Identified Species:
43.33
UniProt:
O00161
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00161
NP_003816.2
211
23354
S116
N
S
P
C
N
V
V
S
K
Q
P
G
P
V
T
Chimpanzee
Pan troglodytes
XP_510337
203
22585
S116
N
S
P
C
N
V
V
S
K
Q
P
G
P
V
T
Rhesus Macaque
Macaca mulatta
XP_001105155
211
23235
S116
N
S
P
C
N
V
V
S
K
Q
P
G
P
V
T
Dog
Lupus familis
XP_535442
211
23395
S116
N
S
P
S
N
V
V
S
K
Q
P
G
R
V
T
Cat
Felis silvestris
Mouse
Mus musculus
O09044
210
23242
S116
N
S
P
S
N
V
V
S
K
Q
P
S
R
I
T
Rat
Rattus norvegicus
O70377
210
23216
S116
S
S
P
S
N
V
V
S
K
Q
P
S
R
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509046
207
22902
K116
N
A
A
D
V
V
S
K
Q
P
G
R
A
T
N
Chicken
Gallus gallus
XP_421159
209
23585
S116
N
S
A
D
H
V
I
S
M
Q
P
R
S
I
N
Frog
Xenopus laevis
NP_001079032
204
22753
S110
W
G
S
K
D
N
D
S
D
V
V
S
K
Q
P
Zebra Danio
Brachydanio rerio
Q5TZ66
204
22839
E121
Q
P
A
R
V
V
D
E
R
E
Q
M
A
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36975
212
23667
G118
T
W
K
G
N
D
D
G
K
V
V
N
N
Q
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999754
212
23995
P123
G
K
V
N
S
H
Q
P
M
R
M
E
D
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMG8
263
29057
E168
K
K
S
E
N
H
K
E
E
R
E
K
L
G
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
97.6
88.6
N.A.
87.1
87.1
N.A.
81.9
76.3
68.2
57.3
N.A.
49.5
N.A.
N.A.
54.7
Protein Similarity:
100
92.8
98
92.8
N.A.
93.8
93.8
N.A.
91.4
84.8
82.4
75.3
N.A.
69.3
N.A.
N.A.
70.7
P-Site Identity:
100
100
100
86.6
N.A.
73.3
66.6
N.A.
13.3
40
6.6
6.6
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
26.6
60
13.3
33.3
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
24
0
0
0
0
0
0
0
0
0
16
0
0
% A
% Cys:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
8
8
24
0
8
0
0
0
8
8
0
% D
% Glu:
0
0
0
8
0
0
0
16
8
8
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
8
0
0
0
8
0
0
8
31
0
8
0
% G
% His:
0
0
0
0
8
16
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
31
0
% I
% Lys:
8
16
8
8
0
0
8
8
54
0
0
8
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
16
0
8
8
0
0
0
% M
% Asn:
54
0
0
8
62
8
0
0
0
0
0
8
8
0
16
% N
% Pro:
0
8
47
0
0
0
0
8
0
8
54
0
24
0
16
% P
% Gln:
8
0
0
0
0
0
8
0
8
54
8
0
0
16
0
% Q
% Arg:
0
0
0
8
0
0
0
0
8
16
0
16
24
0
8
% R
% Ser:
8
54
16
24
8
0
8
62
0
0
0
24
8
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
47
% T
% Val:
0
0
8
0
16
70
47
0
0
16
16
0
0
31
0
% V
% Trp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _